Contact Us

Mailing Address
SSPB Program
Rice University
6500 Main Street, MS-180
Houston, Texas 77030-1400

Physical Address
Ph.D. Program in Systems, Synthetic, and Physical Biology
Suite 170 BioScience Research Collaborative (BRC)
Rice University
6500 Main Street
Houston, Texas 77005


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  • Bacterium from coal mine fire could aid drug targeting
  • Theory lends transparency to how glass breaks
  • Study: Modularity affects human, single-celled migration
  • 'Freeze-frame' proteins show how cancer evolves
  • Enzyme's 'editing' preferences have implications for infertility and cancer

Welcome to the Ph.D. program in Systems, Synthetic, and Physical Biology (SSPB)

Systems, Synthetic and Physical Biology (SSPB) is a new field that combines experimental and theoretical approaches to solve both fundamental and applied problems in the biosciences, biotechnology and medicine. Created and directed by the Institute of Biosciences and Bioengineering at Rice University, SSPB is emerging as one of the most important areas of life sciences of this century. While the past several decades have been dubbed the Information Age, the coming era will likely be a biological one where organisms are engineered to produce new medicines, fuels and materials. In order to reach the potential of engineered biological systems, we must first understand the organizing principles of life. SSPB researchers operate at this interface, aiming to understand the molecular language of life, so that new biological functions can be reliably designed. For more information regarding this program, click here.



Research Spotlight

Protein residues kiss, don't tell
Protein residues kiss, don't tell
This figure shows the predicted structure of a ligand binding domain of protein TM0439 using DCA-fold, a computational method developed by Professor Jose Onuchic and colleagues at the Center for Theoretical Biological Physics. »



David Zong was recently awarded a 2016 NSF Graduate Research Fellowship.